Thyroid-Stimulating Hormone Stimulation Tests in the Bottlenose Dolphin (Tursiops truncatus)
نویسندگان
چکیده
Stimulation of the thyroid with thyroid-stimulating hormone (TSH) is a potentially useful diagnostic dysfunction, but little known about response to TSH stimulation in bottlenose dolphins (Tursiops truncatus). To better characterize dolphin stimulation, five adult participated study. Dolphins voluntarily beached onto padded mat and were given 1.5 mg intramuscular injection human recombinant TSH. Blood samples collected day prior, at multiple intervals of, daily for three days after analyzed via radioimmunoassay free total triiodothyronine (fT3 tT3), thyroxine (fT4 tT4). Significant increases circulating fT3, fT4, tT4 observed peaks occurring all hormones injection; maximal 44%, 47%, 23% each hormone, respectively. Temporal patterns reflected feedback mechanisms countering surge fT3 following stimulation. Though was effective stimulating release, it likely that use or dolphin-derived would enhance clinical utility test, as development antibodies specific
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ژورنال
عنوان ژورنال: Journal of zoological and botanical gardens
سال: 2021
ISSN: ['2673-5636']
DOI: https://doi.org/10.3390/jzbg2020018